New Scientist: Kaposi’s sarcoma, which is caused by a herpes virus, is the most common cancer in sub-Saharan Africa. Up to 70% of those infected die within three years, so early detection is key. The KS-Detect, built by Li Jiang and David Erickson of Cornell University, may provide doctors with that ability. The device focuses sunlight on a microscopic channel etched on a microchip. The channel is filled with a sample from a patient, and the heat from the sunlight drives a polymerase chain reaction (PCR), which amplifies the presence of DNA from the herpes virus that causes the cancer. A dye mixed into the sample glows when the DNA concentration reaches a detectable level. The chip then sends the result to an attached smartphone. Normally, PCR requires a lot of electricity, which is not readily available in much of sub-Saharan Africa. The technology may also be adaptable for other diseases, such as tuberculosis.
His 1988 sketch of how to use Antarctic ice to detect neutrinos led to the IceCube observatory, which made the first detections of high-energy neutrinos in 2013.