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Smart insulin automatically controls glucose levels

FEB 10, 2015

DOI: 10.1063/PT.5.028629

Physics Today

Guardian : Diabetes patients wrestle daily with monitoring their blood sugar levels and determining when to inject insulin and how much. Now researchers have developed an insulin derivative that binds to a protein in blood and automatically activates when blood sugar levels reach a certain threshold. Injected into diabetic mice just once a day, the glucose-responsive insulin kept their blood sugar levels as stable as those in healthy mice. The researchers hope to test the new compound, called Ins-PBA-F, in human patients within two to five years.

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